Ultrasound ionization of biomolecules.
نویسندگان
چکیده
To date, mass spectrometric analysis of biomolecules has been primarily performed with either matrix-assisted laser desorption/ionization (MALDI) or electrospray ionization (ESI). In this work, ultrasound produced by a simple piezoelectric device is shown as an alternative method for soft ionization of biomolecules. Precursor ions of proteins, saccharides and fatty acids showed little fragmentation. Cavitation is considered as a primary mechanism for the ionization of biomolecules.
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ورودعنوان ژورنال:
- Rapid communications in mass spectrometry : RCM
دوره 24 17 شماره
صفحات -
تاریخ انتشار 2010